Surgical intervention of a giant gastric gastrointestinal stromal tumor following neoadjuvant therapy with imatinib

Surgical intervention of a giant gastric gastrointestinal stromal tumor following neoadjuvant therapy with imatinib

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Gastrointestinal stromal tumors (GISTs) treatment has improved remarkably in recent years.However, giant and unresectable lesions could still be challenging, especially from the surgical aspect.We reported a case of a 44-year-old male patient who complained about abdominal pain and distention.Computed tomography scans, upper GI click here endoscopy, and tissue biopsy proved the diagnosis of a giant GIST which was considered unresectable.

With the aid of neoadjuvant imatinib therapy, the tumor shrank tremendously, and we successfully performed princess polly dresses long sleeve en bloc resection with clean margins.Therefore, we suggested combining imatinib therapy and surgery in managing giant and unresectable GIST lesions.